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Now completely up-to-date with the latest research advances, the Seventh Edition retains the distinctive character of earlier editions. Twenty-two concise chapters, co-authored by six highly distinguished biologists, provide current, authoritative coverage of an exciting, fast-changing discipline.
Molecular biology --- Molecular genetics --- Textbooks. --- Moleculaire biologie --- Moleculaire genetica --- Genetic Processes. --- Genetic Structures. --- Genetic Techniques. --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Genetic Counseling --- Genetic Structure --- Structure, Genetic --- Structures, Genetic --- Genetic Processes --- Genetic Structures --- Genetic Techniques --- Molecular Biology --- Genetics --- Genetic Phenomena --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- methods --- 575/12 --- Cytogenetics --- genetica --- moleculaire biologie --- Biologie moléculaire --- Manuels d'enseignement supérieur
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Early detection of colorectal cancers is a significant and relatively recent achievement. Persons who carry genetic mutations linked to hereditary colorectal cancer make up 20% of the patient population. With the advent of molecular genetics and the description of hereditary colorectal cancer syndromes, clinicians and genetic counselors are able to use genetic predisposition testing as an effective and important way to identify patients and families affected by inherited colorectal cancer syndromes. Hereditary Colorectal Cancer is a comprehensive collection that documents not only Familial Adenomatous Polyposis and the Lynch syndrome, but also less understood syndromes, including the Hamartomatous Polyposis Syndromes and MutYH Associated Polyposis. Internationally recognized clinicians and researchers further delve into the evolution and potential of syndromes, genes and molecular alterations that have yet to be defined. Instrumental experts in this field of discovery were carefully selected by the section editors to create this premier reference work for clinicians, scientists and researchers confronted with the treatment and management of hereditary colorectal cancer.
Medicine & Public Health. --- Oncology. --- Surgical Oncology. --- Gastroenterology. --- Medicine. --- Cancer --- Médecine --- Gastroentérologie --- Cancérologie --- Surgery. --- Chirurgie --- Colon (Anatomy) --- Genetic disorders. --- Rectum --- Colorectal Neoplasms --- Adenomatous Polyposis Coli. --- Colorectal Neoplasms, Hereditary Nonpolyposis. --- Genetic Counseling. --- Genetic aspects. --- genetics. --- Colon (Anatomy) -- Cancer. --- Rectum -- Cancer. --- Genetic disorders --- Neoplastic Syndromes, Hereditary --- Intestinal Neoplasms --- Colonic Neoplasms --- Rectal Diseases --- Adenomatous Polyps --- Biology --- Intestinal Polyposis --- Genetic Services --- Colonic Diseases --- DNA Repair-Deficiency Disorders --- Genetics, Medical --- Intestinal Diseases --- Metabolic Diseases --- Gastrointestinal Neoplasms --- Health Services --- Adenoma --- Neoplasms --- Genetic Diseases, Inborn --- Biological Science Disciplines --- Adenomatous Polyposis Coli --- Colorectal Neoplasms, Hereditary Nonpolyposis --- Genetic Counseling --- Genetics --- Neoplasms, Glandular and Epithelial --- Gastrointestinal Diseases --- Digestive System Neoplasms --- Congenital, Hereditary, and Neonatal Diseases and Abnormalities --- Diseases --- Health Care Facilities, Manpower, and Services --- Nutritional and Metabolic Diseases --- Natural Science Disciplines --- Digestive System Diseases --- Neoplasms by Histologic Type --- Health Care --- Neoplasms by Site --- Disciplines and Occupations --- History & Archaeology --- Medicine --- Health & Biological Sciences --- Oncology --- History - General --- Genetic aspects --- Cancer. --- Congenital diseases --- Disorders, Genetic --- Disorders, Inherited --- Genetic diseases --- Hereditary diseases --- Inherited diseases --- Colorectal cancer --- Rectal cancer --- Colon cancer --- Surgical oncology. --- Medical genetics --- Oncology . --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Tumors --- Internal medicine --- Digestive organs --- Excision --- Treatment --- Gastroenterology .
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In 1953 werd door Watson en Crick de structuur van het DNA blootgelegd: dit gaf inzicht in de wijze waarop de erfelijke eigenschappen van een organisme worden 'gecodeerd' en bij elke celdeling doorgegeven. Omstreeks 1975 werd het mogelijk om DNA te 'manipuleren'. De stukjes DNA die een welbepaalde eigenschap tot stand brengen, en die men genen noemt, kan men nu isoleren, identificeren en reproduceren (klonen). In verband met de mens leidt dit samen met andere technieken tot de mogelijkheid om de oorsprong van een groot aantal erfelijke ziekten op te sporen. Door onderzoek van enkele cellen kan men de aanwezigheid van een erfelijke aanleg vaststellen zowel bij de volwassene, het kind, de foetus als bij het embryo. Deze kennis kan heel waardevol zijn, maar ze kan ook ongewenste tot zelfs dramatische gevolgen hebben. Dit boek geeft een inzicht in de mogelijkheden van dit genetisch onderzoek. Tegelijk worden ook de voornaamste ethische vragen gesteld die erdoor worden opgeroepen. (Bron: covertekst)
Human genetics --- Professional ethics. Deontology --- Human medicine --- Erfelijkheidsleer --- Ethique médicale --- Hérédité --- Medische ethiek --- Genetisch onderzoek ; ethiek --- Genetisch onderzoek ; sociale aspecten --- genetica --- erfelijke ziekten --- bio-ethiek --- 174.2 --- 17.023.33 --- 575 --- 061 Ethische problemen --- 094 Biologie --- Erfelijkheid --- Genetica --- 600.2 --- 603.1 --- aangeboren afwijkingen --- erfelijkheidsleer --- ethiek --- genetische diagnose --- genetische test --- maatschappij --- recht --- screening --- 599.2 --- aangeboren afwijkingen (congenitale afwijkingen, hartafwijkingen) --- ethiek (moraal) --- genetisch risico --- prenatale diagnose --- tests --- 010213.jpg --- 61 --- 179.7 --- Beroepsmoraal van de artsen. Medische beroepsethiek --- Génétique --- (zie ook: orthopedie, seksuele ontwikkelingsstoornissen, vaatziekten) --- (zie ook: genetisch advies) --- Conferences - Meetings --- Medical genetics --- Genetic Techniques --- Genetic Counseling --- Genetic Screening --- Moral and ethical aspects --- 174.2 Beroepsmoraal van de artsen. Medische beroepsethiek --- Clinical genetics --- Diseases --- Heredity of disease --- Medical sciences --- Pathology --- Genetic disorders --- Genetic aspects --- Hérédité --- Génétique --- Ethique médicale
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